Jornal de Autacóides Acesso livre

Abstrato

Supplementations of Low Doses of Fish Oil Effects on Clinic and Ambulatory Blood Pressure Levels in Treated Hypertensive Postmenopausal Women Sex Hormones Influence

Diego Muñoz

In the present study, we evaluate the changes that fish oil intake has (as a treatment’s coadjutant) over women’s blood pressure (BP) levels and the possible changes in their sexual hormones. For this reason, two groups were constituted: one group took fish oil during 6 months (SG), and the other group did not (CG). Anthropometric, dietetic, blood pressure and sex hormones controls, including β-estradiol, total testosterone, free testosterone and dehydroepiandrosterone (DHEA), were carried out by RIA techniques at the third and sixth month of starting or not the intake of fish oil, and 3 months after the end of the supplementation. Our study shows improvements in blood pressure only in the group that effectuated the supplementation. In these women, an increase of the total weight was noticed, accompanied by a decrease in the skinfolds. In regard to the hormones, it calls our attention the high DHEA levels in both groups. But the fish oil intake generated a very significant fall in it. Total testosterone also decreased significantly its concentrations. Therefore, we can conclude that the intake of low doses of fish oil produces a decrease in BP, and that the decline in androgenic hormones (DHEA and total testosterone) can play an important role in this decrease.