Jornal de Epigenética Clínica Acesso livre

Abstrato

The Biological Clock and Vascular Disease: Application to Pregnancy

Dimitrios Karoutsos, Petros Karoutsos and Eftychia Karoutsou.

The creation of a biological clock adjusted to way of life synchronizers influences the function of peripheral clocks and by extension, all physiological processes as well as secretion of hormones. Further, disturbance of the function of the biological clock exerts a strong impact on the pathogenesis of several disorders, including diabetes mellitus, insomnia, depression, cardiovascular disease and cancer, linking the pathophysiology of many diseases to one molecular mechanism, the 'out of tune clock'.