Jornal de Cuidados Intensivos e Críticos Acesso livre

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Use of Anti-D in Patients with Severe Dengue: A Case Series

Deven Juneja, Prashant Nasa, Shashank Shekhar, Vikas Saraswat, Arvind Aggarwal and Manisha Arora

Severe dengue fever (SDF) is a potentially fatal disorder with bleeding being a common cause of mortality. Bleeding is generally secondary to thrombocytopenia, which is a common finding in patients with SDF. Intravenous anti-D is an approved therapeutic option in improving platelet counts in the management of idiopathic thrombocytopenic purpura (ITP). It has also been tried in patients with SDF for improving thrombocytopenia. Here we report a series of eight patients with SDF who showed remarkable improvement after administration of anti-D.