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BDNF Serum Levels in Alzheimer’s Disease and Mild ZOYSoǀG Impairment

Kang Joon Lee and Hyun Kim

The >mild cognitive impairment (MCI) group had higher brain-derived neurotrophic factor (BDNF) levels as compared to the Alzheimer’s disease (AD) group, according to a study published by Journal of Psychiatry. Hyun Kim and Kang Joon Lee, Inje University Ilsanpaik Hospital, Goyang, South Korea, examined the differences in the serum BDNF levels in patients with Alzheimer’s disease (AD) and mild cognitive impairment (MCI) and normal controls. BDNF represents a potential neuroprotective agent useful in preventing neurodegeneration, as clearly demonstrated in animal models. In humans, however, the association of BDNF serum levels with the rate of cognitive decline is still unclear