Mohamad Javad Ehsani, Jamileh Mahdavi Jafari, Rasool Choopani, Ghazaleh Heydarirad, Mohamad Kamalinejad and Latif Gachkar
Medicinal plants have been traditionally used as natural medications with healing effects. Scientific assessment of historical documents could be valuable for finding new potential uses for these plants in modern medicine. The liver is a vital organ which plays a key role in metabolism and drug detoxification; if the detoxification functions of the liver are impaired, many disorders will result. Therefore, strengthening liver function with herbal medicines is a fundamental step to achieving or maintaining perfect liver health. Valuable information about medicinal plants and their protective effects on the liver mentioned in the works of Iranian scientists make valuable knowledge available for those who are interested. In the present study, we reviewed traditional books for mention of plants helpful in liver maintenance and the treatment of liver diseases. Any research or articles of modern medicine related to the efficacy of these plants in the gastro-intestinal tract were also collected from the Physician’s Desk Reference (PDR), Google Scholar, and Pub-med. In this paper, we introduce 15 herbal plants used in ITM in order to present an overview of traditional knowledge regarding hepatoprotective plants. Data suggests that Iranian traditional herbs known to be beneficial to liver function could still be an interesting area of study. Therefore, the current work briefly shows the deep knowledge to be found in ITM regarding medicinal plants; however, more clinical trials are needed to prove the efficacy and safety of these herbs for humans.
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