Jornal Europeu de Biologia Experimental Acesso livre

Abstrato

Study of analgesic and anti-inflammatory activity of some 2-substituted acetamido-5-aryl-1,3,4-thiadiazoles

Sanmati K. Jain and Pradeep Mishra

Study of analgesic and anti-inflammatory activity of some synthesized 2-substituted acetamido-5-aryl-1,3,4- thiadiazoles (sixteen compounds) were done. None of the compounds showed any analgesic activity. One of the compound [1/4a1] showed anti-inflammatory activity comparable with the standard drug. Some of the compounds showed moderate activity. Results indicate that substitution in the aryl group result in reduction or loss of activity.